BPC-157 Pen Dosage Protocol

Quick Start

The short version

If you only read one thing, read this. The four cards below are the whole protocol in plain English — the sections that follow just add the detail.

Dosage Chart

Handling

Dosing & Reconstitution Guide

The pen is pre-filled — no reconstitution required. Prime the pen, dial the target dose in mcg, and inject subcutaneously.

Subcutaneous Protocol

Frequency: once or twice daily subcutaneously. Some reference protocols place injections near the injury site; systemic subcutaneous dosing is the most common approach.

Supplies Needed

Plain-English Glossary

Jargon, translated

A quick decoder for the terms you'll see across this page.

Subcutaneous (subQ)

Injected into the fatty layer just under the skin — not into muscle or vein. Easier and less painful than an IM shot.

Reconstitution

Mixing a dry powder with liquid (bacteriostatic water) to turn it into an injectable solution.

Lyophilized

Freeze-dried. The peptide arrives as a dry powder so it stays stable during shipping.

Bacteriostatic water

Sterile water with a tiny amount of preservative that prevents bacteria growth — used to mix peptides.

Units (on an insulin syringe)

The small tick marks on a U-100 syringe. 100 units = 1 mL. Most doses are just a few units.

Half-life

How long it takes your body to clear half of a dose. Guides how often you inject.

Titration

Starting low and slowly increasing the dose so your body can adjust.

Protocol Overview

• Goal: Support tissue repair and recovery research.
• Schedule: Daily subcutaneous injection, once or twice.
• Dose range: 250–500 mcg per administration.
• Storage: Refrigerated, protected from light.

Dosing Protocol

• Start: 250 mcg twice daily.
• Target: 500 mcg total daily as a standard reference dose.
• Timing: Morning and evening for twice-daily schedules.
• Cycle length: 2–6 weeks, then reassess.

Storage Instructions

• Lyophilized product: room temperature, sealed and protected from light. Refrigeration acceptable.
• Reconstituted product: 2–8 °C (35.6–46.4 °F) refrigerated, protected from light.
• Do not freeze reconstituted solution.
• Allow to reach room temperature before administration to reduce injection-site response.

Important Notes

• Use a new sterile syringe for each administration.
• Rotate injection sites (abdomen, thighs, upper arms) to reduce local irritation.
• Discard the vial if the solution becomes cloudy, discolored, or shows particulates.
• Document daily dose and site rotation for consistency.

Mechanism

How This Works

Potential Benefits & Side Effects

• Accelerated tendon, ligament, and muscle recovery reported in preclinical studies.
• Gastrointestinal protective effects, including in NSAID-injury models.
• Reported anti-inflammatory activity.
• Generally well tolerated in reference protocols; human clinical data limited.

Lifestyle Factors

• Combine with progressive loading during rehabilitation research.
• Prioritize sleep and protein intake.
• Avoid excessive alcohol which counters tissue repair.
• Manage inflammation through diet during the protocol.

Injection Technique

1. 1. Attach a fresh pen needle and prime the pen.
2. 2. Clean the injection site with alcohol.
3. 3. Dial the target dose in mcg.
4. 4. Pinch a skinfold; insert at 45–90° subcutaneously.
5. 5. Depress fully, hold 5–10 seconds, withdraw.
6. 6. Discard the pen needle in a sharps container.

References

1. 1

   Sikiric et al. (2018)

   BPC-157 in tissue repair and gastrointestinal research

   View source
2. 2

   Chang et al. (2011)

   BPC-157 promotes tendon-to-bone healing

   View source